ISAN2017・JSNR2017 SCIENTIFIC PROGRAM (English)

 Program at a Glance (Final)

 Program (Oral Sessions)

 Program (Poster Session)

Day 1: Wednesday, August 30

9:00-10:00 ISAN2017 Plenary Lecture 1
Cardiac Receptors: Inhibitory, Excitatory and Everything in Between
Irving Zucker (University of Nebraska, USA)
10:10-12:10 ISAN2017 Symposium 1
New insights into the autonomic nervous system degeneration in multiple system atrophy
Chairs : Tetsutaro Ozawa (Japan)
Masato Asahina (Japan)

  1. Spectrum of the autonomic nervous system degeneration in multiple system atrophy
    Tetsutaro Ozawa (Japan)
  2. Effect of autonomic dysfunction on survival in multiple system atrophy
    Han-Joon Kim (Korea)
  3. New insights into autonomic dysfunction and sleep disorder in MSA
    Pietro Cortelli (Italy)
10:10-12:10 ISAN2017 Symposium 2
Cardiorespiratory control in health and disease
Chairs : Thomas Dick (USA)
Yoshitaka Oku (Japan)

  1. The coupling of cardiorespiratory rhythms in health and disease
    Thomas Dick (USA)
  2. Vagal control of left ventricular excitability and contractility
    Nephtali Marina-Gonzalez (UK)
  3. GABA/Glycine Co-Transmission in the Cardiorespiratory Network
    Swen Hülsmann (Germany)
  4. Amplified respiratory drive to RVLM C1 neurons underlies the altered respiratory-sympathetic coupling and hypertensive phenotype of the SHR rat
    Simon McMullan (Australia)
  5. Brainstem sources of cardiac vagal tone and respiratory sinus arrhythmia
    David Farmer (Australia)
10:10-12:10 ISAN2017 Symposium 3
Autonomic nervous dysfunction in sleep related disorders
Chairs : Yuichi Inoue (Japan)
Keisuke Suzuki (Japan)

  1. Change in heart rate variability associated with periodic limb movements during sleep
    Taeko Sasai-Sakuma (Japan)
  2. Autonomic dysfunction in patients with Narcolepsy-cataplexy
    Yuichi Inoue (Japan)
  3. Autonomic impairments in rapid eye movement sleep behavior disorders
    Takashi Nomura (Japan)
  4. Autonomic changes in sleep apnea syndrome
    Keisuke Suzuki (Japan)
  5. Carotid body chemosensory potentiation is crucial for the autonomic dysfunction and hypertension induced by intermittent hypoxia mimicking obstructive sleep apnea
    Rodrigo Iturriaga (Chile)
12:20-13:20 ISAN2017/JSNR2017 Luncheon Seminar 1 Sponsored by Nihon Medi-Physics Co., Ltd.
Chair : Masahiko Suzuki (Japan)

The Role of Neuronuclear Imaging in the Diagnosis of Lewy Body Diseases
Kenji Ishii

13:30-15:30 ISAN2017 Symposium 4
Recent advances of dysautonomia in Parkinson's disease
Chairs : Hisayoshi Oka (Japan)
Hirohisa Watanabe (Japan)

  1. Pathophysiology of cardiovagal and sympathoneural failure
    Makoto Takahashi (Japan)
  2. Gastrointestinal dysfunction in Parkinson's disease
    Masaaki Hirayama (Japan)
  3. Sudomotor research in Parkinson's disease: past, present, and future
    Masato Asahina (Japan)
  4. Serum uric acid and non-motor symptoms in de novo Parkinson's disease
    Chizuko Toyoda (Japan)
  5. Sudomotor function evaluated by the quantitative sudomotor axon reflex test (QSART) in pure autonomic failure, Parkinson's disease and multiple system atrophy
    Toshimasa Yamamoto (Japan)
  6. Striatal dopamine transporter abnormalities in pure autonomic failure and speculation about the relationship with Lewy bodies
    Makiko Yogo (Japan)
13:30-15:30 ISAN2017 Symposium 5
Participation of glial cells on the cardiorespiratory regulation
Chairs : Yasumasa Okada (Japan)
Jouji Horiuchi (Japan)

  1. Astrocytes are actively involved in respiratory rhythm generation, hypoxic ventilatory responses and pathogenesis of blood pressure elevation
    Yasumasa Okada (Japan)
  2. PACAP, autonomic neurons and glial cells in cardiorespiratory regulation
    Paul Pilowsky (Australia)
  3. Astroglial control of the CNS cardiorespiratory networks
    Nephtali Marina-Gonzalez (UK)
  4. Astrocytes play a crucial role in enhanced sympathetic outflow in heart failure
    Yoshitaka Hirooka (Japan)
  5. Astrocytes play a role in the generation and spread of seizure activity and eventual death in a severely hypoxic condition
    Isato Fukushi (Japan)
  6. Activated astrocytes induce persistence of post-stress blood pressure elevation
    Yohei Hasebe (Japan)
13:30-15:30 ISAN2017 Symposium 6
Oriental Medicine and the Autonomic Nervous System
Chairs : Sae Uchida (Japan)
Hiromi Yamamoto (Japan)

  1. Update on Mechanisms Underlying Peripheral and Central Neural Actions in Acupuncture Autonomic Cardiovascular Regulation
    John Longhurst (USA)
  2. Effect of acupuncture on cardiac and renal sympathetic nerve activities
    Hiromi Yamamoto (Japan)
  3. Spinal mechanism of analgesic effects of acupuncture in the rat models of persistent pain
    Sungtae Koo (Korea)
  4. Mechanism of acupuncture effect on chemotherapy-induced peripheral neuropathy
    Shintaro Ishikawa (Japan)
  5. Validation of electroacupuncture effect for work efficiency
    Hideaki Waki (Japan)
  6. Effect of low-frequency electroacupuncture stimulation into the sacral region on the heart rate and defecation function
    Takuya Suzuki (Japan)
16:00-18:00 ISAN2017 Symposium 7
Catecholaminergic Denervation in Autonomic Synucleinopathies
Chair : David S. Goldstein (USA)

  1. Autotoxicity links catecholaminergic denervation with alpha-synucleinopathy in Lewy body diseases
    David S. Goldstein (USA)
  2. Mechanisms of 3,4-dihydroxyphenylacetaldehyde (DOPAL) toxicity include oligomerization and quinonization of alpha-synuclein
    Yehonatan Sharabi (Israel)
  3. Clinico-pathologic correlations between cardiac sympathetic denervation and alpha-synuclein aggregates in Lewy body diseases
    Satoshi Orimo (Japan)
  4. Sympathetic denervation in synucleinopathies, therapeutic implications
    Horacio Kaufmann (USA)
16:00-18:00 ISAN2017 Symposium 8
Targeting the autonomic nervous system to alleviate inflammatory disorders
Chairs : Bruno Bonaz (France)
Yvette Taché (USA)

  1. Cholinergic modulation of inflammation
    Valentin Pavlov (USA)
  2. The splanchnic anti-inflammatory pathway: The efferent arm of the inflammatory reflex?
    Robin M. McAllen (Australia)
  3. Brain-gut peptides and vagal anti-inflammatory reflex
    Yvette Taché (USA)
  4. Electroceuticals: Vagus nerve stimulation for inflammatory disorders: clinical trials in inflammatory bowel disease, rheumatoid arthritis and post-operative ileus
    Bruno Bonaz (France)
  5. Evaluation of cardiac autonomic functions and C-reactive protein in patients of first myocardial infarction with and without type 2 diabetes mellitus
    Prabhjot Kaur (India)
  6. Chemotherapy-induced enteric neuropathy: mechanisms and potential treatments
    Kulmira Nurgali (Australia)
16:00-18:00 ISAN2017 Symposium 9
Neuro-urology and Autonomic Nervous System: a Diversity of Autonomic Bladder Disorders
Chairs : Ryuji Sakakibara (Japan)
Tatsuya Yamamoto (Japan)

  1. Overview of autonomic bladder disorders
    Jalesh Panicker (UK)
  2. Autonomic bladder disorders in dementia including DLB
    Ryuji Sakakibara (Japan)
  3. Autonomic bladder disorders in stroke
    Tomoyuki Uchiyama (Japan)
  4. Autonomic bladder disorders in Parkinson's disease
    Livia Brusa (Italy)
  5. Autonomic bladder disorders in multiple system atrophy and progressive supranuclear palsy
    Tatsuya Yamamoto (Japan)

Day 2: Thursday, August 31

8:30-9:30 ISAN2017 Plenary Lecture 2
Molecular mechanisms of nociception and thermosensation through TRP channels
Makoto Tominaga (Okazaki Institute for Integrative Bioscience, Japan)
9:40-11:40 ISAN2017 Symposium 10 Sponsored by TSUMURA & CO.
Basic and clinical Insights into oxytocin's effects on augmenting autonomic and anti-stress activity
Chairs : Yoshiyuki Kuroiwa (Japan)
Kevin Shoemaker (Canada)

  1. New insights into mechanisms regulating central release of neuropeptides and their actions on the autonomic nervous system
    Javier Stern (USA)
  2. Tapping the Oxytocin Factor with Kampo - Results from an Open-Label, Single-Arm, Single-Center, Exploratory Study to Evaluate the Safety and Efficacy of TSUMURA Kamikihito Extract Granules for Ethical Use (TJ-137)
    Hiroyuki Kobayashi (Japan)
  3. Antistress effects of Kampo medicine Kamikihito in rats subjected to restraint stress
    Masataka Sunagawa (Japan)
  4. Kamikihito activates oxytocin neurons in the paraventricular nucleus of the hypothalamus
    Kenju Shimomura (Japan)
  5. Effects of traditional kampo medicine, kamikihito on acute/chronic nociceptive stress in rats
    Takashi Maruyama(Japan)
  6. Oxytocin involvement of μ-opioid receptor-mediated analgesia and relationship between functions of oxytocin and kamikihito, a Japanese Kampo medicine
    Yasuhito Uezono (Japan)
9:40-11:40 ISAN2017 Symposium 11
Redefining the sacral autonomic outflow: a debate
9:40-11:40 JSNR2017 Symposium 1
Scientific evidence for the effects of acupuncture, massage and thermal stimulation
Chairs : Mieko Kurosawa (Japan)
Harumi Hotta (Japan)

  1. Peripheral mechanisms and clinical roles of acupuncture and tactile stimulation
    Kenji Kawakita (Japan)
  2. Age-related changes in neuromodulatory control of bladder micturition contractions originating in the skin
    Harumi Hotta (Japan)
  3. Influence of somatic afferent stimulation on neurotransmitter release in the nucleus accumbens and the central nucleus of amygdala in rats
    Mieko Kurosawa (Japan)
  4. Scientific basis for comfortable treatment methods for the face Botulin therapy for the blepharospasm and periocular thermotherapy for fatigue as the comfortable therapeutic method for the face
    Naoto Hara (Japan)
9:40-11:40 JSNR2017 Symposium 2 (Japanese session)
Acquired idiopathic generalized anhidrosis (AIGA)
Chairs : Yoshihiko Nakazato (Japan)
Yoshiki Tokura (Japan)

  1. Clinical characteristics of idiopathic pure sudomotor failure
    Yoshihiko Nakazato (Japan)
  2. AIGA and cholinergic urticarial
    Yoshiki Tokura (Japan)
  3. Investigation of anti-muscarinic acethylcholine receptor autoantibody in patients with AIGA
    Kenji Sano (Japan)
  4. Tropical anhidrotic asthenia: early descriptions of AIGA
    Naotoshi Tamura (Japan)
9:40-10:25 JSNR2017 General Session 1 (Japanese session)
The Central Nervous System 1
Chair : Yasuhiro Hasegawa (Japan)

  1. Relationship between autonomic symptoms and clinical signs in Parkinson's disease: Study using SCOPA-AUT Japanese version
    Takeo Matsubara (Japan)
  2. The relationship between lower urinary tractfunction and 123I- ioflupane scintigraphyin parkinson's disease
    Fuyuki Tateno (Japan)
  3. Gatrointestinal dysfunction in dementia with Lewy bodies: a comparison with Parkinson's disease
    Ryuji Sakakibara (Japan)
10:40-11:25 JSNR2017 General Session 2 (Japanese session)
The Central Nervous System 2
Chair : Shun Shimohama (Japan)

  1. A case of Parkinson disease with reduction of hyperhidrosis in off- period by administration of Rotigotine
    Shigenori Kato (Japan)
  2. Relationships between muscle sympathetic activity and age or disease duration in patients with multiple system atrophy
    Kazumasa Shindo (Japan)
  3. Impaired homeostasis of the autonomic nervous system and radioisotope cisternoscintigraphic abnormality in Japanese females vaccinated against human papilloma virus
    Toshiaki Hirai (Japan)
11:50-12:50 ISAN2017/JSNR2017 Luncheon Seminar 2 Sponsored by Eisai Co., Ltd.
Chair : Shun Shimohama (Japan)

Autonomic dysfunction in patients with Dementia with Lewy bodies
Katsuyoshi Mizukami

13:00-15:00 ISAN2017 Symposium 12
New insights in brain renin-angiotensin-aldosterone system, and its critical role in cardiovascular diseases
Chairs : Frans Leenen (Canada)
Yumei Feng (USA)

  1. Role of CNS aldosterone - MR in cardiovascular disease
    Frans Leenen (Canada)
  2. Emerging role of (pro)renin receptor in autonomic regulation of neurogenic hypertension
    Yumei Feng (USA)
  3. Aminopeptidase a inhibitors as central-acting antihypertensive agents: from discovery to clinical trials
    Catherine Llorens-Cortes (France)
  4. Immunity and sympathetic nervous system in hypertension and heart failure: Role of brain AT1 receptors
    Yohsitaka Hirooka (Japan)
  5. Increased Expression of the (Pro)renin Receptor in the Subfornical Organ of Hypertensive Humans
    Rieko Yamamoto (USA)
  6. Food restriction increases angiotensin II AT1 receptors in the brain of female fisher rats
    Deoclécio A. Chianca Jr. (Brazil)
13:00-15:00 ISAN2017 Symposium 13
Neurovisceral remodeling in disease - Translational potential for Neuromodulation Therapy
Chair : Jeffrey L. Ardell (USA)

  1. Inflammation, oxidative stress, glial cell activation and neurochemical remodeling characterize stellate ganglia from humans with ventricular arrhythmia storm
    Kalyanam Shivkumar (USA)
  2. Developmental influences on sympathetic circuits regulating energy expenditure and susceptibility to obesity
    Lori Zeltser (USA)
  3. Stellate ganglia remodeling in cardiac disease - foundational aspects of neural network remodeling
    David Paterson (UK)
  4. Novel signaling pathways in cardiopulmonary systems in health and disease
    Stephen Lewis (USA)
  5. Molecular Understanding of the Interaction between Heart and Brain in Mental and Physical Stress-Induced Cardiomyopathy (Takotsubo)
    Keiichi Fukuda (Japan)
14:30-15:00 JSNR2017 Chairman's LectureJSNR2017
Chair : Akira Takahashi (Japan)

Circumventricular Organs Dysregulation Syndrome (CODS)
Yoshiyuki Kuroiwa (Japan)

15:30-17:30 ISAN2017 Symposium 14
Recent Developments in Autonomic Circulatory Control During Exercise
Chairs : Erin Howden (Australia)
Justin Lawley (USA)

  1. Metaboreflex Regulation of Sympathetic Activity at Altitude in Lowlanders and Sherpa
    Craig Steinback (Canada)
  2. Regulation of sympathetic tone at rest and activity - implications on functional capacity and survival
    William Cornwell III (USA)
  3. Centrally acting angiotensin converting enzyme inhibitor and antioxidants attenuate the central sympathetic outflow during dynamic exercise in humans
    Gilbert Moralez (USA)
  4. Lack of ipsilateral metaboreflex from contracting muscle: evidence from directing recording of sympathetic nerve activity to contracting muscle
    Vaughan Macefield (Australia)
  5. Chondroitin sulfate suppresses the low-pH induced mechanical response in thin muscle afferents of rats
    Norio Hotta (Japan)
  6. Water deprivation does not enhance pressor responses to handgrip exercise in humans or sciatic nerve stimulation in rats
    Joseph Watso (USA)
15:30-17:30 ISAN2017 Symposium 15
Pinpointing the origins of baroreflex gain and set-points
Chair : John P. Horn (USA)

  1. Where in the CNS should we look, and how does it work?
    Robin M. McAllen (Australia)
  2. Baroreflex sensitivity and set-point: It starts with the afferents
    Mark W. Chapleau (USA)
  3. Interaction between intracranial pressure and the sympathetic nervous system; a new link between the brain and the cardiovascular system
    Simon Malpas (New Zealand)
  4. Lessons from single synapses in sympathetic ganglia
    John P. Horn (USA)
  5. An arterial sensory unit is not only a transducer but also a processor that provides signals to regulate hemodynamics
    Jerry Yu (USA)
15:30-17:30 JSNR2017 Symposium 3
Cutting edge of immune-mediated autonomic neuropathies
Chairs : Shunya Nakane (Japan)
Haruki Koike (Japan)

  1. Perspectives on immune-mediated neuropathies
    Takashi Kanda (Japan)
  2. Anti-ganglionic acetylcholine receptor antibodies and immune mediated neuropathies in Japan
    Shunya Nakane (Japan)
  3. Acute autonomic and sensory neuropathy
    Haruki Koike (Japan)
  4. Dysautonomia in Guillain-Barré syndrome
    Kenichi Kaida (Japan)
15:30-17:30 JSNR2017 Symposium 4 (Japanese session)
Change of autonomic nervous system associated with vision due to stress
Chair : Naoto Hara (Japan)

  1. The effect of the digital devise with prolonged screen time on near response and on autonomic nervous system
    Naoto Hara (Japan)
  2. The role of autonomic nerve system in the regulation of ocular blood flow in response to the stress
    Taiji Nagaoka (Japan)
  3. Eyelid opening with trigeminal proprioceptive evocation activates sympathetically innervated sweat glands and ventromedial prefrontal cortex via the locus coeruleus
    Kiyoshi Matsuo (Japan)
  4. Effect of occlusal discomfort on the autonomic nervous system
    So Koizumi (Japan)
  5. VR and the Autonomic Nervous Function-Efforts to estimate the influences of stressful stimuli under VR environment by using autonomic laboratory tests
    Takehiko Bando (Japan)
15:30-17:30 JSNR2017 Symposium 5 (Japanese session)
The digestive organs and the autonomic nervous system
Chairs : Masashi Yoneda (Japan)
Masahiko Nakamura (Japan)

  1. Stress-Related Pathophysiology of Autonomic Nervous System in Irritable Bowel Syndrome
    Shin Fukudo (Japan)
  2. Medullary neuropeptides activated vagal-mediated gastric protection against injury
    Hiroshi Kaneko (Japan)
  3. Central glucagon like peptide-1 regulates gastrointestinal motor functions through autonomic nervous systems
    Yukiomi Nakade (Japan)
  4. The effect of vagotomy on gastric MALT lymphoma development in Helicobacter suis-infected mouse model
    Masahiko Nakamura (Japan)
  5. Gastrointestinal hormones in neurodegenerative autonomic disorders
    Tetsutaro Ozawa (Japan)

Day 3: Friday, September 1

8:30-9:30 ISAN2017 Plenary Lecture 3
How reliable is cerebral blood flow to map changes in neuronal activity?
Edith Hamel (McGill University, Canada)
9:40-11:40 ISAN2017 Symposium 16
Assessment of Human Autonomic Cardiovascular Control: New Approaches to Answer Old Questions
Chair : Can Ozan Tan (USA)

  1. Identification of cortical and subcortical sites involved in the generation of muscle sympathetic nerve activity through MSNA-coupled fMRI
    Vaughan G. Macefield (Australia)
  2. Assessment of cardiac autonomic control by ambulatory electrocardiogram (ECG)
    Junichiro Hayano (Japan)
  3. Methodological Approaches to Assessment of Autonomic Control of Peripheral Circulation
    Kevin Shoemaker (Canada)
  4. Approaches to Quantification of Autonomic Control of Cerebral Circulation
    Can Ozan Tan (USA)
  5. Demonstration of blood pressure dysregulation controversy in supine hypertension with neurogenic orthostatic hypotension syndrome
    Jan Galuszka (Czech)
9:40-11:40 ISAN2017 Symposium 17
Central circuitries controlling autonomic physiological response to stressful events
Chairs : Youichirou Ootsuka (Australia)
Rodrigo Alvim Cunha de Menezes (Brazil)

  1. New insights on the lateral habenula: its contribution to the emotional hyperthermia
    Youichirou Ootsuka (Australia)
  2. New insights on Amygdala: The role of Basomedial Amygdala on the regulation of the autonomic and behavioral response to social stress
    Rodrigo Alvim Cunha de Menezes (Brazil)
  3. Contribution of serotonergic neurons in the defense response
    Tomoyuki Kuwaki (Japan)
  4. Anxiety and Fear: Quantifying the Mind Using EKG with mDFA
    Toru Yazawa (Japan)
  5. Physiological correlates of emotional control in school-aged children
    Cynthia Y.Y. Lai (Hong Kong)
9:40-11:40 JSNR2017 Symposium 6
Basic and clinical insights into new hypothalamic syndrome caused by human papilloma virus vaccination
Chairs : Yoshiyuki Kuroiwa (Japan)
Kusuki Nishioka (Japan)

  1. A study on our novel murine model of Humanpapillomavirus-associated Neuroimmunopathic Syndrome (HANS)
    Toshihiro Nakajima (Japan)
  2. A unique symptomatic spectrum of autonomic, endocrine, cognitive, and locomotive impairments after receiving the Human Papillomavirus (HPV) vaccination: pathophysiological and therapeutic studies
    Shumpei Yokota (Japan)
  3. Autoimmune encephalopathy and autonomic failure after human papilloma virus vaccination
    Hiroshi Takashima (Japan)
  4. Clinical characteristics and treatment of Human papillomavirus (HPV) vaccination associated with neuro-immunopathic syndrome
    Kusuki Nishioka (Japan)
9:40-11:40 JSNR2017 Symposium 7
Leaders targeting next stage researches for autonomic nervous system
Chair : Hiroshi Kiyama (Japan)

  1. Reconstitution of organs and their functional connections using human pluripotent stem cell-derived autonomic nerves
    Yasuyuki Kida (Japan)
  2. Emerging mechanisms for body-fluid homeostasis
    Takeshi Hiyama (Japan)
  3. Liver-brain axis: participation in emotional behaviors via vagal nerves
    Masayuki Sekiguchi (Japan)
  4. Glial cell-based development and function of the enteric nervous system
    Hideki Enomoto (Japan)
9:40-10:40 JSNR2017 General Session 3 (Japanese session)
The Periferal Nervous System and others 1
Chair : Satoshi Iwase (Japan)

  1. Effects of aging on heart rate variability in Japanese women
    "The evaluation of Heart Rate Variability during ergometer loading"

    Yuka Goto (Japan)
  2. Effects of radium thermal spa bathing on the peripheral reactive hyperemia index and autonomic function of the heart
    Mayura Shimura (Japan)
  3. Measuring quality of sleep and autonomic nervous function in healthy Japanese women
    Miki Sato (Japan)
10:40-11:25 JSNR2017 General Session 4 (Japanese session)
The Periferal Nervous System and others 2
Chair : Naotoshi Tamura (Japan)

  1. Cardiac and peripheral vasomotor autonomic functions in transthyretin familial amyloid polyneuropathy
    Haruki Koike (Japan)
  2. Pure Autonomic Failure with Sick Sinus Syndrome
    Mieko Sugiura (Japan)
  3. The Clinical Study for adenylate cyclase activity in Neurally Mediated Syncope
    Tomoyoshi Komiyama (Japan)
11:50-12:50 ISAN2017/JSNR2017 Luncheon Seminar 3 Sponsored by Sanofi K.K.
Chair : Norihiro  Suzuki (Japan)

Fabry disease: neurological involvement and therapy
Alessandro Burlina (Italy)

13:00-15:00 ISAN2017 Symposium 18
Physiologic Mechanisms of Human Cerebrovascular Regulation in Health and Disease: An Integrated Perspective
Chairs : J. Andrew Taylor (USA)
Can Ozan Tan (USA)

  1. Neurogenic and Regional Mechanisms of Cerebral Autoregulation in Health and Disease
    Can Ozan Tan (USA)
  2. Cerebrovascular Control in Response to Changes in Blood Gases
    Shigehiko Ogoh (Japan)
  3. On the road to neurovascular coupling in the short-tailed fruit bat, Carollia perspicillata
    Rena Orman (USA)
  4. Cerebral blood flow during infusion of dobutamine
    Takuro Washio (Japan)
13:00-15:00 ISAN2017 Symposium 19
Challenges to reveal autonomic functions by novel techniques
Chairs : Yoichi Ueta (Japan)
Hironobu Morita (Japan)

  1. Sleep, hypoxia, arousal and cardiovascular control: Mechanistic insights from rodents using optogenetics
    Peter Burke (Australia/USA)
  2. C1 neurons mediate a stress-induced protection of renal ischemia/reperfusion injury
    Chikara Abe (Japan)
  3. Novel transgenic rat lines regulating the neuronal activity in rat vasopressin neuron by using Optogenetics and DREADDs technology
    Mitsuhiro Yoshimura (Japan)
  4. Measurement of neuronal activity in conscious animal by in vivo photometory system
    Akira Yamashita (Japan)
  5. Tetanic stimulation of the hypothalamus evokes persistent excitation in the ventrolateral medulla: Spatiotemporal dynamics
    Yosuke Kono (Japan)
  6. The difference of the autonomic nerve (AN) balance between the heart rate variability (HRV) and papillography
    Go Ito (Japan)
13:00-14:00 JSNR2017 Special Lecture 1
Chair : Mieko Kurosawa (Japan)

Smooth muscles and their nerves: forms and doubts
Giorgio Gabella (UK)

14:00-14:45 JSNR2017 Special Lecture 2
Chair : Mieko Kurosawa (Japan)

A history of autonomic neuroscience researches in Japan
Tadaaki Mano (Japan)

14:50-15:30 JSNR2017 Special Lecture 3
Chair : Nobuo Araki (Japan)

Impact of autonomic dysfunction on familial amyloid neuropathy
Yukio Ando (Japan)

15:55-17:55 ISAN2017 Symposium 20
Autonomic nervous system disorders in Migraine and Trigeminal autonomic cephalalgias (TACs)
Chairs : Nobuo Araki (Japan)
Hisanori Kowa (Japan)

  1. Autonomic nervous system disorders in mgraine
    Nobuo Araki (Japan)
  2. Autonomic dysfunction in trigeminal autonomic cephalalgias (TACs)
    Hisanori Kowa (Japan)
  3. Short-lasting unilateral neuralgiform headache
    Noboru Imai (Japan)
  4. Cluster headache like symptoms due to sinusitis
    Takao Takeshima (Japan)
15:55-17:55 ISAN2017 Symposium 21
Neuro-immune physiology and pathophysiology
Chairs : Makoto Kadowaki (Japan)
Wouter de Jonge (Netherlands)

  1. Daikenchuto, a Japanese herbal medicine inhibited macrophages infiltration through α7nACh receptor on intestnal macrophages in postoperative ileus
    Masatoshi Hori (Japan)
  2. Various TLRs ligands activate isolated mouse enteric neurons and PLC is involved in TLR4 signaling pathway
    Hanako Ogata (Japan)
  3. Adrenergic nerves control lymphocyte trafficking and adaptive immune responses
    Kazuhiro Suzuki (Japan)
  4. Regulation of mucosal immunity via vagal and sympathetic pathways
    Wouter de Jonge (Netherlands)
  5. Sympathetic intestinal innervation regulates murine dextran sodium sulphate (DSS)-induced colitis
    Rose Willemze (Netherlands)
  6. Pathogenesis of the sigmoid diverticular disease is manifested by the calcitonin gene-related peptide expression
    A. G. Pauza (Lithuania)
15:55-17:55 JSNR2017 Symposium 8
Sensation and central autonomic regulation
Chairs : Akiko Arata (Japan)
Fusao Kato (Japan)

  1. The Kölliker-Fuse nucleus of the pontine parabrachial complex: An interface for the coordination of breathing and orofacial behavior
    Mathias Dutschmann (Australia)
  2. Functional morphology of the ventral part of the caudate putamen originating from the parabrachial nucleus: Neural circuits connecting between feeding behavior and gustatory and visceral senses
    Haruki Iwai (Japan)
  3. Vocalization-respiration mode switching mechanism exists in the Parabrachial nucleus
    Akiko Arata (Japan)
  4. Breathing rhythm and emotions
    Yuri Masaoka (Japan)
15:55-17:55 JSNR2017 Symposium 9 (Japanese session)
Segmental and/or unilateral hyperhidrosis: clinical characteristics and etiologies
Chairs : Yoko Inukai (Japan)
Hiroshi Saito (Japan)

  1. Pathogenesis of segmental and/or unilateral hyperhidrosis: estimation based on a part of the physiological mechanism of the skin pressure-sweating reflex
    Yoko Inukai (Japan)
  2. Segmental hyperhidrosis with dysesthesia: possible irritation of autonomic and sensory systems
    Hiroshi Saito (Japan)
  3. Idiopathic segmental anhidrosis and harlequin syndrome
    Yoshihiko Nakazato (Japan)
  4. Compensatory sweating after thoracic sympathectomy
    Hidehiro Yamamoto (Japan)
15:55-16:55 JSNR2017 General Session 5 (Japanese session)
Basic Autonomic Research
Chair : Shoshiro Okada (Japan)

  1. Sodium-glucose co-transporter (SGLT) inhibitor has a therapeutic effect on diabetic enteric neuropathy in mice fed a high-fat diet
    Satoshi Shimo (Japan)
  2. Differential roles of adrenoceptors in the hypothalamic paraventricular nucleus in corticotropin-releasing factor-induced sympathetic activation in rats
    Naoko Yamaguchi (Japan)
  3. Possible involvement of autonomic nervous system in upregulation of arginine vasopressin-eGFP fusion gene in the hypothalamus after bilateral nephrectomy in the transgenic rat
    Hiromichi Ueno (Japan)
  4. Propagation of injected alpha-synuclein fibril from the gut to the brainstem
    Norihito Uemura (Japan)
16:55-17:55  JSNR2017 General Session 6 (Japanese session)
Reflex responses
Chair : Sae Uchida (Japan)

  1. Effect of direct current electric-acupuncture on heart rate
    Kiyoshi Tamai (Japan)
  2. Responses of blood pressure to stroking of the skin in healthy young subjects under the condition of elevated sympathetic nervous system
    Kunihiro Arimoto (Japan)
  3. Effect of moxibustion stimulation to the body surface on gastric motility in anesthetized rats
    Tomomi Narushima (Japan)
  4. Differences in accommodative response and pupillary constriction of near response with refractive errors
    Noriko Onozato (Japan)
18:20-20:20 Poster discussion

Day 4: Saturday, September 2

8:30-9:30 ISAN2017 Plenary Lecture 4
Novel central pathways regulating brown adipose tissue (BAT) thermogenesis
Shaun Morrison (Oregon Health and Science University, USA)
9:40-11:40 ISAN2017 Symposium 22
Roles of peripheral serotonergic receptors and purinergic receptors
Chairs : Miyako Takaki (Japan)
Gary M. Mawe (USA)

  1. Pro- and anti-inflammatory roles of 5-HT and its receptors in the gut
    Gary M. Mawe (USA)
  2. Micro-coordination of pacemaker potentials may characterize functional states of gut motility
    Shinsuke Nakayama (Japan)
  3. Neuronal anti-inflammatory signaling via 5-HT4 receptor stimulation in small intestine
    Masatoshi Hori (Japan)
  4. Signal transmission via purinergic receptors to sensory nerves from mechanical stimulation of bone or joints
    Keiji Asada (Japan)
  5. Serotonin modulates synchronization between respiration and fetal movement in the pons
    Hirotaka Ooka (Japan)
9:40-11:40 ISAN2017 Symposium 23 Sponsored by Eisai Co., Ltd.
Autonomic dysfunction in dementia
Chairs : Hitoshi Shimada (Japan)
Shigeki Hirano (Japan)

  1. Autonomic dysfunction in dementia - overview
    Masaaki Hirayama (Japan)
  2. Neuropathological background of autonomic dysfunction in dementia
    Yuko Saito (Japan)
  3. Autonomic and cognitive impairment based on basal ganglia dysfunction
    Kaoru Takakusaki (Japan)
11:50-12:50 ISAN2017/JSNR2017 Luncheon Seminar 4 (Japanese session) Sponsored by Sumitomo Dainippon Pharma Co.,Ltd.
Chair : Masahiko Suzuki (Japan)

The Clinical Course of Parkinson's disease-from Preclinical to Late Stage-
Hiroshi Nagayama (Japan)

13:00-15:00 ISAN2017 Symposium 24
Infection fever, neurogenic fever and psychogenic fever: how are they different?
Chair : Kazuhiro Nakamura (Japan)
Kiyoshi Matsumura (Japan)

  1. Mediators of infection-induced fever and associated mood alteration
    David Engblom (Sweden)
  2. Central mechanism of neurogenic fever
    Kiyoshi Matsumura (Japan)
  3. Difference in central circuit mechanisms of infection-induced and psychogenic fever
    Kazuhiro Nakamura (Japan)
  4. Location and characteristics of the central thermal sudomotor pathways in human spinal cord
    Hiroshi Saito (Japan)
  5. The activation of intraoral TRPV1 may induce selective brain cooling to protect the brain from overheating: a hypothesized function of gustatory sweating
    Yoko Inukai (Japan)
13:00-15:00 ISAN2017 Symposium 25
Interactions between Pain and the Autonomic Nervous System
Chairs : Harumi Hotta (Japan)
Mathieu Piché (Canada)

  1. Neural mechanisms involved in the noxious stress-induced inhibition of ovarian estradiol secretion
    Sae Uchida (Japan)
  2. Optogenetic and chemogenetic dissection of the essential role of the parabrachial nucleus in the nociception-emotion link
    Fusao Kato (Japan)
  3. Neurovascular coupling during nociceptive processing in the spinal cord of the rat
    Mathieu Piché (Canada)
  4. An anti-plexin D1 autoantibody is associated with neuropathic pain and autonomic symptoms
    Takayuki Fujii (Japan)
  5. Skin coldness and painful cold: the common symptom in patients with clinically suspected small fiber neuropathy in Korea
    Eunbin Cho (Korea)